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Oxygen Sensing in Cancer and Metabolism

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Changes in oxygen levels lead to shifts in the cellular metabolome and transcriptome. This is especially relevant in the context of cancer where the tumor microenvironment can often be hypoxic and lead to the activation of programs that augment the pathogenic potential of the disease. Reciprocally, metabolic dysfunction in cancer can affect oxygen consumption and the production of reactive oxygen species that feed into oxygen sensing pathways. Please join us to hear about the latest work on the connections between oxygen sensing, metabolism, and cancer from Celeste Simon, Navdeep Chandel, and Amato Giaccia.

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Presenters

Presenter
Dr. Navdeep S Chandel
Depart. of Medicine and Cell Biology
Northwestern University
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Presenter
Dr. M. Celeste Simon
Scientific Director
University of Pennsylvania
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Presenter
Dr. Amato Giaccia
Prof. of Radiation Oncology
Stanford School of Medicine
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Presenter
Moderator:
Brian Plosky
Senior Scientific Editor
Molecular Cell
Presenter
Moderator: Dr. Nikla Emambokus
Editor
Cell Metabolism
Presenter
Moderator:
Angela Messmer-Blust
Scientific Editor
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