Exploring Cellular Processes with Super-Resolution Microscopy

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3D super-resolution microscopy shows the inner structure of the cell at higher resolutions than ever. This enables a new era of discovery in understanding cell functions.

In this webinar, Kristen Whalen, Ph.D., at the Scripps Institute of Oceanography at University of California San Diego, will talk about how she used Applied Precision’s DeltaVision OMX platform in imaging membrane dynamics in sea urchin embryos.

Whalen can quantitatively describe the fine-scale (nanometers) movements of multidrug transporters required for activation of efflux activity. Multidrug transporters are best known for their contributions to chemotherapeutic resistance through the efflux of anticancer drugs from metastatic cancers. Until now, relatively little was known about how the fine-scale traffic and positioning of these proteins at the cell surface influenced drug transporter function.

This work is among the first to apply quantitative super-resolution imaging to study these surface structure-function relationships. GE Healthcare Life Sciences is proud to introduce Applied Precision’s DeltaVision OMX platform now with the revolutionary Blaze SIM Module. Ian Clements of Applied Precision will talk about:

Comparisons of different super-resolution imaging techniques
Super-resolution imaging using the DeltaVision OMX system
Live-cell super-resolution imaging

Cell Reports papers related to the webinar can be found in this Cell Reports Collection.

Who should attend: Those interested in super-resolution microscopy

Presenters

Moderator:
Simone Groothuis
Publisher Cellular Signalling Journal

Kristen Whalen
Postdoctoral Fellow
Scripps Institute of Oceanography
View Bio

Ian Clements
Applied Precision - A GE Healthcare Company
DeltaVision OMX Product Manager
View Bio

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Are you looking to expand your cellular analysis capability?
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Not at this time.
Yes, with HCA.
Yes, with confocal microscopy.
Yes, with widefield microscopy.
Yes, with super-resolution microscopy.
Yes, with flow cytometry.
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DV Elite Imaging System
DeltaVision OMX Super-resolution microscopy system
IN Cell Analyzer for high content analysis

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