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Synthetic and naturally occurring macromolecules are often complex mixtures of many molecules differing in molar mass, as well as in other structural features such as comonomer content and distribution, branching, or end-group functionalization. One-dimensional separation methods like size exclusion chromatography (SEC) or interaction chromatography (IC) are usually not sufficient to resolve such complex mixtures due to limitations of the separation mechanisms. Given the multidimensional complexity of such samples, hyphenated separation methods are increasingly applied for their characterization.

In a 2D-LC separation, separation is first achieved by one feature (e.g. comonomer content) followed by a second separation by another property, such as size. This allows determination of the correlation between different structural features such as the dependence of chemical composition on molar mass.

In this webinar, our speakers will present the concept, different approaches for technical realization, and industrial applications of 2D-LC in polymer separations.

Key learning objectives

• Explore the multidimensional heterogeneity of polymers
• Learn how to perform 2D-LC separations of polymers
• Discover additional information that can be gained by 2D-LC separations

Who should attend?

• Polymer researchers
• Scientists interested in polymer and macromolecular analysis,
• Material scientists
• Scientists and practitioners involved in complex separation problems

View other webinars in this series here:

Part 1: Unraveling the Intricacies of Size Exclusion Chromatography – Strength and Limitations

Part 2: Detection in Gel Permeation Chromatography /Size Exclusion Chromatography

Part 3: Characterization of Macromolecules by SEC-Light Scattering

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.