Biomarker discovery for lysosomal storage disorders using a metabolomic approach

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Biomarker discovery for lysosomal storage disorders using a metabolomic approach

Available On Demand

Overview

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High-accuracy mass spectrometry is a powerful tool to discover biomarkers, allowing the diagnosis, monitoring and follow-up of different diseases. During this webinar, Dr. Michel Boutin, Technical Director of the Waters-CHUS Expertise Centre in Clinical Mass Spectrometry, will discuss the different steps of untargeted/semi-targeted metabolomic studies, such as sample collection, sample preparation, sample analysis, data analysis and structural elucidation, along with strategies to bypass potential pitfalls.

Different tools to structurally elucidate targeted biomarkers will also be discussed and examples of metabolomic studies that led to the discovery of new biomarkers for genetic diseases will be presented.

Key learning objective:

  • Learn how to perform untargeted/semi-targeted metabolomic studies to discover novel biomarkers for genetic diseases by mass spectrometry.

Who should attend?
  • Clinical scientists, medical technologists & biomedical scientists
  • Decision makers interested in tools to advance biomarker discovery
  • Clinical researchers with an interest in analytical method development
  • Clinicians with an interest in inborn errors of metabolism
  • Post-doctoral and postgraduate scientists with an interest in analytical method development
Certificate of attendance
All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes.

Webinar speaker:
Dr. Michel Boutin
Technical Director of the Waters-CHUS Expertise Centre in Clinical Mass Spectrometry

Technical Director, Waters-CHUS Expertise Centre in Clinical Mass Spectrometry, Sherbrooke, QC, Canada and adjunct professor, Department of Pediatrics, Division of Medical Genetics, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Michel Boutin is a mass spectrometry specialist. He received his master’s and Ph.D. degrees from Montreal University for research projects related to airborne monitoring of contaminants in the workplace. He did a first postdoctorate in industrial hygiene at McGill University (Montreal, QC), a second postdoctorate at the Université Pierre et Marie Curie (Paris, France) on the analysis of proteins related to cancer by mass spectrometry (ESI and MALDI), and a third postdoctorate at the Institute for Research in Immunology and Cancer (Montreal, QC) in metabolomics. He worked for 2 years as a scientific assistant for a proteomic platform (Université Laval, QC). Since 2011, he is the technical director of the Water-CHUS Expertise Centre in Clinical Mass Spectrometry (Clinical Research Centre-CHUS, Sherbrooke, QC). 

Presenters

Presenter
Michel Boutin, Ph.D.
Technical Director
Waters-CHUS Expertise Centre in Clinical Mass Spectrometry
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Presenter
Moderator: Sarah Thomas
Editorial Team
SelectScience
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